A study published in JAMA in March of 2026 says psychedelics are no better than antidepressants for depression. Here’s why the headline misses key context on side effects, duration, and healing.

Ketamine dosing explained: IV, IM, intranasal, and oral routes compared: bioavailability, clinical research, and how dosing decisions are made.

Dr. Weiner explores a recently published secondary analysis of a trial that compared ketamine to electroconvulsive therapy (ECT) for treatment-resistant depression, finding that ECT and ketam!ne both effective long-term, with moderate to severe depression patients having faster improvement with ketamine, and very severe depression responding faster to ECT.

Dr. Weiner reviews a recently published deep dive into ketamine's use as a rapid antidepressant, exploring its potential and pitfalls and highlighting therapeutic effects, ethical concerns, and safety issues in treatment-resistant depression.

Research unveils the mechanisms behind ketamine's ability to induce altered brain oscillations, offering profound insights into its therapeutic potential and the nature of consciousness itself.